meperidine

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analgesic

 [an″al-je´zik]
1. relieving pain.
2. pertaining to analgesia.
3. an agent that relieves pain without causing loss of consciousness.
narcotic analgesic opioid analgesic.
nonsteroidal antiinflammatory analgesic (NSAIA) nonsteroidal antiinflammatory drug.
opiate analgesic (opioid analgesic) any of a class of compounds that bind with a number of closely related specific receptors (opioid receptors) in the central nervous system to block the perception of pain or affect the emotional response to pain; such compounds include opium and its derivatives, as well as a number of synthetic compounds, and are used for moderate to severe pain. Chronic administration or abuse may lead to dependence.

meperidine

(mĕ-per´ĭ-dēn) an opioid analgesic, used as the hydrochloride salt as an analgesic and an anesthesia adjunct.

meperidine

(mə-pĕr′ĭ-dēn′)
n.
A synthetic opioid, C15H21NO2, used in its hydrochloride form as an analgesic and sedative. Also called pethidine.

meperidine

An IV opioid analgesic with an active metabolite, normeperidine.
 
Route
Parenteral, oral.
 
Pharmacologic effects
Potent blocker of pain messages to the brain.

Contraindications
Co-administration with MAOI antidepressants (may cause dizziness, lightheadedness, nausea); ritonavir.

T1/2
2–5 hours for relief of moderate to severe pain.
 
Therapeutic range
200–800 ng/mL, meperidine; 130–480 ng/mL, normeperidine.
 
Toxic range
> 7 mg/L.
 
Specimen
Random urine, serum.
 
Method
Urine, TLC; serum, GC.

meperidine

Demerol Pain management An IV agonist opioid analgesic, with an active metabolite, normeperidine Route Parenteral, oral Pharmacologic effects Powerful blocker of pain messages to the brain Contraindications Not coadministered with MAOI antidepressants–may cause dizziness, lightheadedness, nausea. See Opioids.

meperidine

See PETHIDINE.

meperidine

a centrally acting analgesic with spasmolytic properties equal to those of atropine. Has little hypnotic effect and relieves pain without reducing consciousness, muscular activity, coordination or responsiveness of the special senses. An addictive drug for humans. Called also pethidine.