methyltransferase

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methyltransferase

 [meth″il-trans´fer-ās]
any enzyme that catalyzes transmethylation.

meth·yl·trans·fer·ase

(meth'il-trans'fer-ās),
Any enzyme transferring methyl groups from one compound to another.

methyltransferase

/meth·yl·trans·fer·ase/ (-trans´fer-ās) any of a group of enzymes that catalyze the transfer of a methyl group from one compound to another.

meth·yl·trans·fer·ase

(meth'il-trans'fĕr-ās)
Any enzyme transferring methyl groups from one compound to another.
Synonym(s): transmethylase.

methyltransferase

any enzyme that catalyzes transmethylation.
References in periodicals archive ?
To explain this discrepancy and to investigate other mechanisms that may cause the decrease in H3K9me3, we examined the levels of Jmjd2a, the histone demethylase that catalyzes de methylation of trimethylated H3K9 and H4K20 (Couture et al.
The azoles inhibit ergosterol biosynthesis through their interactions with the enzyme lanosterol demethylase, which is responsible for the conversion of lanosterol to ergosterol in the fungal cell membrane, leading to the depletion of ergosterol in the membrane (30,31).
Similar DNA hypermethylation effects are caused through the loss of function of TET2, a demethylase enzyme that is also mutated in leukemia.
These enzymes include peptidylarginine deiminase enzymes and amine oxidase- and JmjC domain--containing histone demethylase enzymes.
Demethylase activity is directed by histone acetylation.
Enzo Life Sciences will also introduce new enzyme drug discovery kits for histone deacetylases (HDACs) and lysine-specific demethylase 1 (LSD1), emerging targets for cancer and other diseases.
Crystal structure of cytochrome P450 14alpha -sterol demethylase (CYP51) from Mycobacteriurn tuberculosis in complex with azole inhibitors.
DAS acted as a competitive inhibitor of N-dimethylnitrosamine demethylase activity (84).
html) filed a US patent application that relates to a new, novel method to detect demethylase enzyme activity.
The two phytochemicals, hydroxytyrosol and oleuropein, were discovered to inhibit cancer cells and inhibit the activity of lysine specific demethylase 1 (LSD1), an enzyme shown to have increased expression in multiple cancer types.
And it is the first known demethylase discovered for a strategic methylation point on the tail of histone 4 known as H4K20, which other evidence suggests plays a critical role in gene expression and regulation and in the DNA damage response.
The oral presentation titled "Lysine-Specific Histone Demethylase, LSDI (KDM1A) As a Novel Therapeutic Target in Myeloproliferative Neoplasms," outlines the beneficial effects including a reduction in mutant cells and reversal of fibrosis by inhibiting LSD1 in a well-established mouse model of myelofibrosis.