porphobilinogen synthase

(redirected from Delta-Aminolevulinate Dehydratase)
Also found in: Acronyms.

por·pho·bi·lin·o·gen syn·thase

a liver enzyme catalyzing the formation of porphobilinogen and water from two molecules of δ-aminolevulinate, an important reaction in porphyrin biosynthesis; inhibited by lead in cases of lead poisoning; a deficiency of this enzyme results in elevated levels of δ-aminolevulinate and results in neurologic disturbances.

porphobilinogen synthase

References in periodicals archive ?
Delta-aminolevulinate dehydratase polymorphism and blood lead levels in Chinese children.
Effect of the delta-aminolevulinate dehydratase polymorphism of the accumulation of lead in bone and blood in lead smelter workers.
Influence of the common human delta-aminolevulinate dehydratase polymorphism on lead body burden.

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