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CCR5
(redirected from Delta 32)

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
CCR5
A chemokine receptor; defects in its structure caused by genetic mutation cause the progression of AIDS to be prevented or slowed.
Mentioned in: AIDS


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He also stopped the use of important drugs to treat AIDS, anticipating that the new, mutated cells would ward off virus on their own Huetter revealed that some people carry a genetic mutation called Delta 32 that apparently makes them resistant to HIV infection.
Known as Delta 32, it occurs in a gene called CCR5, on Chromosome 3.
The CC chemokine receptor 5 (CCR5) delta 32 variant results in a non-functional form of the chemokine receptor, which is incapable of binding beta chemokines (RANTES, MIP-1alpha, MIP-1beta).
 
 
 
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