Delayed hypersensitivity reactions
to subcutaneously injected heparin are relatively common and present as eczematous plaques at injection sites (Anders & Trautmann, 2013).
Aspartame, for instance, is metabolized to formaldehyde, which has been associated with type 4 delayed hypersensitivity reactions
It is fundamental to allogeneic- and synergeneic-graft rejection, graft-versus-host reactions and the delayed hypersensitivity reactions [10,21].
Reports of direct demonstration of delayed hypersensitivity reactions in lower vertebrates are generally sparse; Barters and Sommer  and, Sin et al.
Macrophage are responsive to a number of lymphokines that induce their growth differentiation and activation; since lymphokines are released by primed lymphocytes, produced chiefly by T-lymphocytes, on contact with an antigen , and the demonstration of a lymphookine mediated reaction in this study strongly supported the existence of T like lymphocytes in Tilapias and that the fish is capable of delayed hypersensitivity reactions.
2), (3) For those with food allergies that are not IgE-mediated and associated with delayed hypersensitivity reactions, estimates are more difficult to determine.
Type IV reactions may also be involved in some delayed hypersensitivity reactions, such as celiac disease, in which there is a reaction to the gliadin fraction of grains and wheat gluten.
We conducted a prospective study of 60 patients in a tertiary care referral center to ascertain the status of cell-mediated immunity as determined by delayed hypersensitivity reactions in patients with nasopharyngeal carcinoma (NPC) or allergic rhinitis.
Because a delayed hypersensitivity reaction to a previously sensitized antigen occurs, patients who had not been previously vaccinated with bacille Calmette-Guerin (BCG) were not eligible for this study.
Non-IgE-mediated inflammatory responses to food antigens that are driven by T cells and other immune cell types have been implicated in delayed hypersensitivity reactions
affecting both babies and adults (1,4).
Epithelioid granulomatous reaction patterns have been reported with delayed hypersensitivity reactions to silica, zirconium, palladium, aluminium, and beryllium.
After extravasation of the intravenous hirudin site, the patient developed a delayed hypersensitivity reaction that histologically showed an epithelioid granulomatous infiltrate.