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deiodinase

   Also found in: Wikipedia 0.03 sec.
deiodinase
an enzyme that deiodinates two of the iodinated amino acids (iodothyrosines) within the thyroid gland. Selenium-dependent deiodinase I converts thyroxine (T4) to triiodothyronine (T3), the more active thyroid hormone.


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Naturally occurring selenoproteins such as thioredoxin reductases, GSH-Px, SeP, iodothyronine deiodinase types I, II, and III, and others with specific functions have also been identified (Kryukov et al.
The roles of serum selenium and selenoproteins on mercury toxicity in ... by Chai, Zhifang / Environmental Health Perspectives
1997), along with another 33 TH-regulated genes, including deiodinase and other metabolic enzymes.
A rapid, physiologic protocol for testing transcriptional effects of ... by Demenneix, Barbara A. / Environmental Health Perspectives
Effects of microsomal enzyme inducers on outer-ring deiodinase activity toward thyroid hormones in various rat tissues.
Thyroid-hormone--disrupting chemicals: evidence for dose-dependent ... by DeVito, Michael J. / Environmental Health Perspectives
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