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neoplasm |
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neoplasm /neo·plasm/ (ne´o-plazm) tumor; any new and abnormal growth, specifically one in which cell multiplication is uncontrolled and progressive. Neoplasms may be benign or malignant.
Neoplasm An abnormal formation of tissue; for example, a tumor. Mentioned in: Intestinal Polyps, Multiple Endocrine Neoplasia Syndromes, Multiple Myeloma, Parathyroid Scan neoplasm [nē′ōplaz′əm] Etymology: Gk, neos + plasma, formation neoplasm (nēˈ·ō·plaˑ·z n an abnormally growing tissue in the body, such as cancer. neoplasm, n (tumor), an abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of the normal tissues. It persists in the same excessive manner after cessation of the stimuli that evoked the change. Benign and malignant forms are recognized. See also neoplasia and tumor. neoplasm 1. a tumor. 2. any new and abnormal growth, specifically one in which cell multiplication is uncontrolled and progressive. Neoplasms may be benign or malignant. Neoplasms of particular organs and of particular cell types are to be found under their individual headings, e.g. pharyngeal, adenocarcinoma. benign neoplasm a neoplasm having none of the characteristics of a malignant neoplasm (see below), i.e. it grows slowly, expands without metastasis, and usually does not recur. neoplasm fever due to extensive necrosis in rapidly growing tumors. histoid neoplasm a neoplasm whose cells and organization resemble those of the tissue from which it is growing. malignant neoplasm a neoplasm with the characteristics of anaplasia, invasiveness and metastasis. organoid neoplasm a neoplasm whose cellular architecture resembles that of some organ in the body. transmissible neoplasm a neoplasm capable of being transmitted between individuals. Includes bovine viral leukosis, avian leukosis, rous sarcoma complex, marek's disease, canine transmissible venereal tumor, squamous cell carcinoma of cattle, and canine viral papillomatosis. neoplasm Oncology 'An abnormal mass of tissue, the growth of which exceeds and is uncoordinated with that of normal tissue and persists in the same excessive manner after cessation of the stimuli evoking the change'; an
autonomous proliferation of cells, benign or malignant. See Cancer, Doubling time, Intraductal papillary-mucinous neoplasm of pancreas, Metastases, Papillary & solid neoplasm of pancreas.
Neoplasm classifications
Behavior Benign, borderline or malignant
Degree of differentiation Well-differentiated, ie the neoplastic cell simulates its parent or progenitor cell or poorly-differentiated, ie the neoplastic cell is bizarre and ''ugly', as defined by pathologic
criteria'
Embryologic origin Epithelial–eg adenocarcinoma, squamous cell carcinoma, lymphoproliferative–eg leukemia, lymphoma, mesenchymal–eg sarcoma, histiocytosis, neural crest–eg carcinoid tumor, some small cell
carcinomas, etc
Gross appearance Well-circumscribed or infiltrative; benign neoplasms, usually slow-growing, well-circumscribed, often with a fibrous capsule, and are symptomatic only if they compromise a confined space, eg massive meningioma of the cranial
cavity, or encirclement of vital blood vessels; malignancies are often aggressive with ↑ mitotic activity, bizarre cells, necrosis and invasion of adjacent structures and have metastatic potential
Patient discussion about Degree of differentiation. Q. what is carcinoid tumors? I had my appendix removed and the doctor came in the room very shocked and said it was full of carcinoid tumors. Im scared to get them somewhere else. A. i think the shock was not to find carcinoid tumors in the appendix...it's your age...you usually find this tumors at people over 60... i think the next stage is colonoscopy, to look for more, not that you have more, just to make sure. but didn't the Doctor told you that? i would look for a consultation with a gastro specialist about it.. Q. Is it safe to have sex with a woman with cancer of the uterus? My 45-years old wife was told she have cancer in the uterus, and will have an operation soon. Meanwhile, should we use a condom during sex? Can the tumor pass from her to me (like AIDS or HPV)? A. unless the cancer has lots of bleeding, you don't need to use condoms. but if your wife would undergo an operation, maybe you need to be off-of-that-sex 1-2 days prior to operation day, just to make sure there's no super infection that will bother the operation plan. Q. How do doctors find out if a tumor is malignant? What procedure is done to see if a tumor is malignant? Is a simple MRI enough to make that conclusion? A. It depends on what type of tumor- what organ is involved and how big is it. Sometimes a simple blood test can show high levels of tumor markers and sometimes just the shape and size of it on CT or MRI can hint that it is a malignant tumor. However, the final answer can only be by biopsy or removal of the tumor and microscopic tests (that's the pathology work-up the doctors send). Read more or ask a question about Degree of differentiationHow to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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There was no correlation between the degree of differentiation and TTF-1 expression, and no distinguishing histologic features of the positive tumors were noted. All the world over, the music of the more primitive of the uncivilized races may be said to move on parallel lines, and it is only as tribes and nations rise somewhat in the scale of nature that their music begins to display any marked degree of differentiation. Olfactory neuroblastomas are graded I through IV on the basis of the degree of differentiation and the presence or absence of a neural stroma, mitotic figures, and necrosis. |
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