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decompensation
(redirected from Decompensating)

   Also found in: Wikipedia 0.04 sec.
decompensation /de·com·pen·sa·tion/ (de?kom-pen-sa´shun)
1. inability of the heart to maintain adequate circulation, marked by dyspnea, venous engorgement, and edema.
2. in psychiatry, failure of defense mechanisms resulting in progressive personality disintegration.

de·com·pen·sa·tion (dkm-pn-sshn)
n.
1. Failure of the heart to maintain adequate blood circulation, marked by labored breathing, engorged blood vessels, and edema.
2. The appearance or exacerbation of a mental disorder due to failure of defense mechanisms.

decompensation (dē·kmˈ·pen·sāˑ·shn),
n 1. a persistent (yet reversible, in some cases) pattern of dysfunction, in which homeostatic mechanisms are overwhelmed, either in part or completely.
2. postural pattern in which the musculoskeletal system indicates dysfunctional ad-justments as a result of a physical anomaly, such as shortened leg.

decompensation
failure of compensation.

cardiac decompensation
inability of the heart to maintain adequate circulation; it is marked by dyspnea, venous engorgement, cyanosis and edema.

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It is indicated for the treatment of patients suffering from acute hepatic encephalopathy due to decompensating liver disease and drug overdose.
The company has two lead product candidates, CPC-111 (currently in Phase II trials for acute complications of angioplasty, cardiac surgery, decompensating heart failure and sickle cell crisis) and CPC-211 (currently in Phase II clinical trials for ischemic stroke and closed head injury).
The company has two lead product candidates, CPC-111 (currently in Phase II trials for patients with decompensating heart failure, and cardiac bypass) and CPC-211 (currently in a Phase II trial in ischemic stroke).
 
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