Amanita phal·loi·des (f -loi d z )n. A mushroom containing toxins such as phalloidine and amanitin that cause gastroenteritis and necrosis of the liver and kidneys. |
Amanita Phalloides
A mushroom which, along with related species—A bisporigera, A verna, A virosa—is the most common cause of fatal mushroom poisonings
Mechanism The major toxins are amanatins, a series of closely related heat-stable cyclic octapeptides, which inhibit RNA polymerase in liver cells
Management Symptomatic-rehydration, IV glucose, instillation of 100 g of activated charcoal per os, mannitol to prevent oliguria; 50% of late-treated patients die
Mechanism The major toxins are amanatins, a series of closely related heat-stable cyclic octapeptides, which inhibit RNA polymerase in liver cells
Management Symptomatic-rehydration, IV glucose, instillation of 100 g of activated charcoal per os, mannitol to prevent oliguria; 50% of late-treated patients die
Amanita phalloides
Toxicology A mushroom which, with related species–A bisporigera, A verna, A virosa are the most common cause of fatal mushroom poisonings Clinical After a 12-hr latency, N&V, abdominal colic,
severe watery diarrhea; this is followed by a 24-hr latency period, then–if the amount ingested was significant—by fatal hepatitis and renal failure Management Symptomatic-rehydration, IV glucose, instillation of 100 g of activated
charcoal per os, mannitol to prevent oliguria; 50% of late-treated Pts die. See Poisonous mushroom.
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