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alkylation
(redirected from Dealkylation)

   Also found in: Encyclopedia, Wikipedia 0.06 sec.
alkylation /al·kyl·a·tion/ (al″kĭ-la´shun) the substitution of an alkyl group for an active hydrogen atom in an organic compound.
al·kyl·a·tion (lk-lshn)
n.
A process in which one or more alkyl groups are substituted for hydrogen atoms in an organic compound.

alkylation,
a chemical reaction in which an alkyl group is transferred from an alkylating agent. When such organic reactions occur with a biologically significant cellular constituent such as deoxyribonucleic acid, they result in interference with mitosis and cell division.


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Because organisms are exposed to various sources of organotins and these chemicals undergo dealkylation in vivo, cells in tissues are generally exposed to a mixture of organotins.
This suggests that the dealkylation of ethylmercury is much more extensive than that of MeHg.
The CYP1A1 and CYP2B1 activities in lung microsomes were determined by monitoring the dealkylation of EROD or PROD, respectively.
 
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