daunorubicin

daunorubicin /dau·no·ru·bi·cin/ (daw″no-roo´bĭ-sin) an anthracycline (q.v.) antibiotic used as an antineoplastic; administered as the hydrochloride salt or as a liposome-encapsulated preparation of the citrate salt.

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daunorubicin [daw″no-roo´bĭ-sin]

an antitumor antibiotic of the anthracycline family, produced by a strain of Streptomyces coeruleorubidus and having antimitotic, cytotoxic, and immunosuppressive effects. As the hydrochloride salt it is administered intravenously in the treatment of acute lymphoblastic leukemia and acute myelogenous leukemia. As a liposome-encapsulated preparation of the citrate salt, it is administered intravenously in the treatment of advanced Kaposi's sarcoma associated with acquired immunodeficiency syndrome (AIDS).

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daunorubicin

an anthracycline antibiotic produced by a strain of Streptomyces coeruleorubidus that is closely related to doxorubicin and has antimitotic, cytotoxic and immunosuppressive effects.

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daunorubicin

Oncology An antineoplastic antibiotic isolated from Streptomyces spp, effective against ALL and AML, and used for other CAs Toxicity Dose-related BM suppression, mucositis, alopecia, severe local reaction with extravasation