Danysz phenomenon

Da·nysz phe·nom·e·non

(dah'nishz),
reduction of the neutralizing effect of an antitoxin when toxin is mixed with it in divided portions, rather than adding the same total quantity of toxin in one step.

Danysz phenomenon

(don′ish)
[Jean Danysz, Polish-born Fr. pathologist, 1860–1928]
A phenomenon that illustrates the reversibility of precipitation of antibody and antigen complexes. When a specified amount of diphtheria toxin is added all at once to an antitoxin serum, the mixture is nontoxic; but when the same quantity of toxin is added in portions at about 30-min intervals, the mixture is toxic.

Danysz,

Jean, Polish pathologist in France, 1860-1928.
Danysz phenomenon - reduction of the neutralizing effect of an antitoxin when toxin is mixed with it in divided portions.
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