danazol


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danazol

 [dan´ah-zol]
a synthetic androgen that suppresses the ovarian-pituitary axis by inhibiting the release of gonadotropins from the pituitary gland; administered orally for treatment of endometriosis, fibrocystic disease of the breast, hereditary angioedema, and gynecomastia.

da·na·zol

(dā'nă-zol),
A synthetic steroid used to treat endometriosis, fibrocystic breast disease, and angioedema. Indirectly reduces estrogen production by lowering levels of follicle-stimulating hormone and luteinizing hormone.

danazol

/dan·a·zol/ (dah´nah-zōl) an anterior pituitary suppressant used in the treatment of endometriosis, fibrocystic breast disease, and gynecomastia and the prophylaxis of attacks of hereditary angioedema.

danazol

[dan′əzol]
a synthetic androgen that acts to suppress the output of gonadotropins from the pituitary, suppress ovarian hormone production, and directly block ovarian hormone receptors.
indications It is prescribed in the treatment of endometriosis, fibrocystic breast disease, and hereditary angioedema when alternative hormonal therapy is ineffective, contraindicated, or intolerable.
contraindications Genital bleeding; cardiac, liver, or kidney dysfunction; or known hypersensitivity to this drug prohibits its use. It is not prescribed during pregnancy or lactation.
adverse effects Among the most serious adverse reactions are muscle spasms, nausea, weight gain, acne, edema, oily skin, voice changes, and other androgenic effects.

danazol

Endocrinology A non-virilizing anabolic androgen used to manage HANE, fibrocystic breast disease, endometriosis, and possibly autoimmune hemolytic anemia and autoimmune thrombocytopenia, but may mediate immune thrombocytopenia Adverse effects Weight gain, edema, acne, hirsutism, deepening of voice, clitorimegaly, menometrorrhagia, ↓ HDL-C, ↑ liver enzymes, peliosis hepatis, benign intracranial HTN. See Hereditary angioneurotic edema.

da·na·zol

(dā'nă-zol)
A synthetic steroid used to treat endometriosis, fibrocystic breast disease, and angioedema. Indirectly reduces estrogen production by lowering levels of follicle-stimulating hormone and luteinizing hormone.

da·na·zol

(dā'nă-zol)
A synthetic steroid used to treat endometriosis, fibrocystic breast disease, and angioedema.

danazol

(dan´əzol´),
n brand name: Danocrine;
drug class: androgen, α-ethinyl testosterone derivative;
action: decreases FSH and LH output;
uses: endometriosis, prevention of hereditary angioedema, fibrocystic breast disease.

danazol

an attenuated androgen that suppresses the ovarian-pituitary axis by inhibiting the release of gonadotropins from the pituitary gland. In animals, it has been used in the treatment of immune-mediated disorders, including anemia and thrombocytopenia.
References in periodicals archive ?
3 132b DANAZOL TAB/CAP - Each tab/cap to contain; Danazol 200mg.
The effect of danazol on menorrhagia, coagulation mechanisms, haematological indices and body weight.
Is oil of evening primrose effective for mastalgia, a comparison with danazol.
Short term treatment of uterine fibromyoma with danazol.
The biochemistry of human endometrium after two regimens of postcoital contraception: a dl norgestrel/ ethinylestradiol combination or danazol.
A woman taking danazol will typically not ovulate or get regular periods.
Currently, it is considered that the treatment of NDDH is the same as that of classic Sweet's syndrome, with many therapies having been suggested in the literature; namely: corticosteroids, dapsone, potassium iodide, colchicine, clofazimine, azathioprine, danazol, tetracyclines, and cyclosporine (3).
The rats were randomly divided into 5 groups: sham-operation control group (Group A), model group (Group B), CHM combined with acupuncture group (Group C), CHM group (Group D), Danazol group (Group E) with 8 rats in each group.
Oral administration of low dose danazol to patients with DME is safe with no evidence of serious adverse events.
El danazol actua a traves de varios mecanismos, inhibiendo a nivel hipotalamico la liberacion de gonodotropinas, lo que inhibe el brote de LH y de FSH a mediados del ciclo, inhibe las enzimas de la sintesis de esteroides en el ovario, ademas de los efectos androgenitos.
Danazol - this drug, at a dose of 200mg daily, blocks ovulation and has a success rate of nearly 80% but you can gain weight.
Past surgical history included dental fillings, which had been carried out uneventfully with a six-week course of pre-procedure danazol.