danaparoid


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danaparoid

 [dah-nap´ah-roid]
an agent used as the sodium salt in prophylaxis of pulmonary thromboembolism and deep venous thrombosis.

danaparoid

/da·nap·a·roid/ (dah-nap´ah-roid) an antithrombotic used as the sodium salt in the prophylaxis of pulmonary thromboembolism and deep venous thrombosis.

danaparoid

an anticoagulant.
indications It is used to prevent vein thrombosis in hemodialysis, stroke, elective surgery for malignancy or total hip replacement, and hip fracture surgery.
contraindications Hypersensitivity to this drug, sulfites, or pork products prohibits its use. Other factors that contraindicate its use include hemophilia, leukemia with bleeding, thrombocytopenia, purpura, cerebrovascular hemorrhage, cerebral aneurysm, severe hypertension, and other severe cardiac disease.
adverse effects Life-threatening side effects include hemorrhage and thrombocytopenia. Hypersensitivity reactions and rash are additional adverse effects.

danaparoid

Orgaran® Cardiovascular disease An injectable, LMW heparin that ↓ risk of postop DVT and PE after hip replacement surgery; it is also used for heparin-induced thrombocytopenia. See Deep vein thrombosis, Heparin-induced thrombocytopenia, Pulmonary embolism.
References in periodicals archive ?
Optimizing risk stratification in portal vein thrombosis after splenectomy and its primary prophylaxis with antithrombin III concentrates and danaparoid sodium in liver cirrhosis with portal hypertension," Journal of the American College of Surgeons, vol.
Danaparoid was used previously with success, but this product is no longer available.
The present in vitro experiments were planned to determine whether the DTIs lepirudin and argatroban and the predominantly factor Xa inhibitors enoxaparin, danaparoid, and fondaparinux could interfere with the result of LA testing based on dPT.
Kasabach-Merritt syndrome associated with giant liver hemangioma; the effect of combined therapy with danaparoid sodium and tranexamic acid.
He was infused large-volume crystalloid fluids and diuretics for HC along with danaparoid for prevention of clots in the bladder, but his hematuria progressed to grade IV and MGH from day 17.
11) Because ofthe high rate ofthrombosis in patients with HIT, anticoagulation should be switched from heparin to an alternative anticoagulant; a direct thrombin inhibitor such as lepirudin (recombinant hirudin), bivalirudin, argatroban, fondaparinux, or danaparoid.
The effects of unfractionated heparin, low molecular weight heparin and danaparoid on the thromboelastogram (TEG): an in-vitro comparison of standard and heparinase-modified TEGs with conventional coagulation assays.
Effect of danaparoid sodium on proteinuria, von Willebrand factor, and hard exudates in patients with diabetes mellitus type 2.
13) However, warfarin should be initiated while the patient is receiving danaparoid or a thrombin-specific inhibitor--with at least 5 days of overlapping therapy recommended.
Danaparoid is derived from porcine intestinal mucosa containing 84% heparin sulfate, dermatan sulfate, and chondroitin sulfate.
Heparin-induced thrombocytopenia--therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4-heparin complexes.
Bu durumda antikoagulan tedavi seceneklerini danaparoid, lepuridin, argatroban ve bir sentetik dusuk molekul agrilikli heparin (DMAH) olan fondaparinux olusturur [4].