DDB2

(redirected from Damage-specific DNA-binding protein 2)

DDB2

A gene on chromosome 11p12-p11 that encodes a protein necessary for the repair of UV-light-damaged DNA, which is the small subunit of DNA damage-binding protein (a heterodimer composed of a large (DDB1) and a small subunit) that functions in nucleotide-excision repair.

Molecular pathology
DDB2 mutations have been tentatively linked xeroderma pigmentosum complementation group E (XPE).
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