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dalfopristin

   Also found in: Wikipedia 0.01 sec.
dalfopristin /dal·fo·pris·tin/ (dal-fo´pris-tin) a semisynthetic antibacterial used in conjunction with quinupristin against various gram-positive organisms, including vancomycin-resistant Enterococcus faecium.
dalfopristin
[dalfo′pristin]
a semisynthetic antibacterial effective against a variety of gram-positive organisms. It is used in conjunction with quinupristin in the treatment of serious bacteremia caused by vancomycin-resistant Enterococcus faecium and complicated skin and skin structure infections caused by Streptococcus pyogenes or methicillin-sensitive Staphylococcus aureus; it is administered intravenously.

dalfopristin [dal-fo´pris-tin]
a semisynthetic antibacterial effective against a variety of gram-positive organisms. It is used in conjunction with quinupristin in the treatment of serious bacteremia caused by vancomycin-resistant Enterococcus faecium and complicated skin and skin structure infections caused by Streptococcus pyogenes or methicillin-sensitive Staphylococcus aureus; administered intravenously.

dalfopristin
See Synercid®.


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Based on the Naranjo probability scale, the likelihood that quinupristin dalfopristin caused the anemia and reticulocytopenia is probable.
Resistance to erythromycin, clindamycin, tetracycline, and virginiamycin [an analog to quinupristin/ dalfopristin, which is used to treat vancomycin-resistant Enterococcus faecium infections in humans (Johnson and Livermore 1999)] was investigated.
Although, as a streptogramin B, quinupristin is cross-resistant with macrolides and lincosamides, dalfopristin is a streptogramin A and not part of this resistance pattern.
 
 
 
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