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miconazole |
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miconazole /mi·con·a·zole/ (mi-kon´ah-zōl) an imidazoleantifungal agent used as the base or the nitrate salt against tinea and cutaneous or vulvovaginal candidiasis.
miconazole (mīkon´ n brand names: Monistat, Monistat IV; drug class: antifungal; action: alters cell membranes and inhibits fungal enzymes; uses: coccidioidomycosis, candidiasis, cryptococcosis, paracoccidioidomycosis, fungal meningitis; IV used for severe infections only. miconazole nitrate (topical),
n brand names: Micatin, Monistat-7; drug class: antifungal; action: interferes with fungal cell membrane, which increases permeability, leaking of nutrients; uses: tinea pedis, tinea cruris, tinea corporis, tinea versicolor, vaginal or vulvar C. albicans. miconazole an imidazole antifungal agent used topically as the nitrate in the treatment of fungal and yeast infections of the skin.
antifungal agent Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent.
miconazole A broad-spectrum antifungal, used topically for cutaneous candidiasis, IV for systemic mycosis–candidiasis, coccidioidomycosis, paracoccidioidomycosis, intrathecally for cryptococcal meningitis Adverse effects Pruritus
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