DMD(redirected from DXS269)
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Doctor of Dental Medicine.
Abbreviation for Doctor of Dental Medicine; Duchenne muscular dystrophy.
DMDDoctor of Dental Medicine.
Dentariae Medicinae Doctor (Doctor of Dental Medicine)
DMDA gene on chromosome Xp21.2 that encodes dystrophin, a protein that anchors the extracellular matrix to the cytoskeleton via F-actin. It is the ligand for dystroglycan and a central component of the dystrophin-glycoprotein complex, which accumulates at the neuromuscular junction and at various synapses in the peripheral and central nervous systems and has a structural function in stabilising the sarcolemma. It plays a key role in signalling events and synaptic transmission. DMD is a highly complex gene, containing at least eight independent, tissue-specific promoters and two polyA-addition sites; it is the largest gene found in nature (2.4 Mb).
Defects of DMD cause both Duchenne- and Becker-type muscular dystrophy.
DMDAbbrev. for Diploma in Dental Medicine.
Duchenne muscular dystrophy (DMD)
The most severe form of muscular dystrophy, DMD usually affects young boys and causes progressive muscle weakness, usually beginning in the legs.
Mentioned in: Muscular Dystrophy
Abbreviation for doctor of dental medicine.