DST


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.

DST

abbreviation for dexamethasone.

DST

A gene on chromosome 6p12.1 that encodes dystonin, a cytoskeletal linker protein which integrates intermediate filaments, actin and the microtubule cytoskeleton network, and is required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional reticulum.

DST isoform 3 plays a structural role in assembling hemidesmosomes of epithelial cells; it anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes and is required for regulating keratinocyte polarity and motility; it mediates integrin ITGB4 regulation of RAC1 activity. DST isoform 6 is required for bundling actin filaments around the nucleus. DST isoform 7 regulates the organisation and stability of the microtubule network of sensory neurons to allow axonal transport.

Molecular pathology
Defects of DST cause hereditary sensory and autonomic neuropathy type 6.
References in periodicals archive ?
DOT, charged with evaluating the plan of extending DST into March, reported in 1975 that "modest overall benefits might be realized by a shift from the historic six-month DST (May through October) in areas of energy conservation, overall traffic safety and reduced violent crime.
Separated by time and distance, members of the DST from Hawaii, Japan and Okinawa deployed to Camp Hialeah in Korea to join forces with their team members in Pusan for the three-day exercise early February.
In the US, DST's wholly-owned subsidiary will acquire State Street's ownership interest in BFDS by delivery to State Street of approximately 2m shares of State Street common stock owned by DST for total consideration of USD 157.
DST Global Solutions is a 390 person business with USD60 to USD65 million in annual revenues, 90% of which comes from EMEA and Asia Pacific.
DST Systems' obligation to consummate its previously announced repurchase of common stock from the Argyros Group at a price of USD 82.
A DST may cause particular concerns should the property not perform well, because the trustee's authority to work-out problems (and thus vary the investment) is very limited.
In the DST method, processability and the properties of the coated paper are affected by the temperature-dependent viscoelastic properties of the latex binder.
DST is a firm of engineers, scientists and contractors that provides geoscience and related services like geotechnical and environmental engineering, materials sciences, highway engineering, green building technologies, mining engineering, surface and groundwater studies, aggregate resources, ground stabilization and drilling technologies.
6 May 2014 -- Missouri US-based insurance software provider DST Systems Inc (NYSE: DST) said that the Argyros Family Trust and certain of its affiliates intend to offer for sale in an underwritten secondary offering USD 450m of shares of DST Systems' common stock pursuant to DST Systems' shelf registration statement filed with the Securities and Exchange Commission.
Under the agreement, DST will nominate Lynn Dorsey Bleil and John W.
Upon the close of this transaction, DST will own over 99,9% of Mail.