SALL4

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SALL4

A gene on chromosome 20q13.2 that encodes a zinc finger transcription factor, which may be involved in musculoskeletal embryogenesis.

Molecular pathology
SALL4 mutations cause Duane-radial ray syndrome.
References in periodicals archive ?
The DRRS uses two complementary approaches to identifying capability for JFCOM and other force managers.
The DRRS also allows force managers to trace inventories of individuals in high-demand occupations such as law enforcement and civil engineering or who possess rare skills such as speaking Farsi.
The capabilities of these support organizations should be reflected in DRRS because they hold important data on assets or services that are available to sustain operations.
Because DRRS aims to take full advantage of existing information systems, it will not require a unit to enter data for ESORTS that it has already entered in another system.
That is why task and mission assessments in DRRS are the professional judgments of commanding officers and are not algorithmically derived.
Recommendation: To address the risks facing DOD in its acquisition and deployment of DRRS, and to increase the chances of DRRS meeting the needs of the DOD readiness community and Congress, the Secretary of Defense should direct the Deputy Secretary of Defense, as the Chair of the Defense Business Systems Management Committee, to reconsider the committee's recent approval of DRRS planned investment for fiscal years 2009 and 2010, and convene the Defense Business Systems Management Committee to review the program's past performance and the DIO's capability to manage and deliver DRRS going forward.
In this regard, the Secretary should direct the Deputy Secretary to solicit the advice and recommendations of the DRRS Executive Committee.
Recommendation: The Secretary of Defense, through the appropriate chain of command, should take steps to ensure that DRRS requirements are effectively developed and managed with appropriate input from the services, Joint Staff, and combatant commanders, including (1) establishing an authoritative set of baseline requirements prior to further system design and development; (2) ensuring that the different levels of requirements and their associated design specifications and test cases are aligned with one another; and (3) developing and instituting a disciplined process for reviewing and accepting changes to the baseline requirements in light of estimated costs, benefits, and risk.
Recommendation: The Secretary of Defense, through the appropriate chain of command, should take steps to ensure that the DRRS program office is staffed on the basis of a human capital strategy that is grounded in an assessment of the core competencies and essential knowledge, skills, and abilities needed to perform key DRRS program management functions, an inventory of the program office's existing workforce capabilities, and an analysis of the gap between the assessed needs and the existing capabilities.
Recommendation: The Secretary, through the appropriate chain of command, should take steps to ensure that DRRS is developed and implemented in a manner that does not increase the reporting burden on units and addresses the timeliness, precision, and objectivity of metrics that are reported to Congress.