DRD2


Also found in: Acronyms.

DRD2

A gene on chromosome 11q23 that encodes G protein-coupled dopamine receptor D2, which inhibits adenylyl cyclase.

Molecular pathology
Defects in DRD2 are associated with myoclonic dystonia.
References in periodicals archive ?
The data also shows a strong association of the minor alleles (A1 and B1) of the DRD2 with cocaine dependence, suggesting that a gene located on the q22-q23 region of chromosome 11 confers susceptibility to this drug disorder.
Interestingly, for the first time we also found that the activation in a part of the brain called the striatum was increased when those with the variant in FTO looked at high-calorie foods, but this depended on which variant of the other gene DRD2 they possessed.
As the recession progressed, mothers with the crucial DRD2 variant apparently adjusted enough to tougher economic times to allow for a return to pre-recession parenting practices, Lee proposes.
Genotyping for the DRD2 polymorphism was carried out using a MassARRAY iPLEX platform.
David's own recent work has focused on two candidate genes: the dopamine DRD2 receptor and the serotonin transporter gene.
This triggers feelings of satisfaction and pleasure, which are stimulated by the DRD2 gene.
Psychologists from the University of Bonn have found a connection between such everyday lapses and the DRD2 gene.
Washington, Mar 22 ( ANI ): Psychologists from the University of Bonn have found a connection between everyday cognitive lapses and the DRD2 gene.
Genetic variables could include serotonergic genes (serotonergic receptors [5HT2a]; serotonin transporter 5HTlPR); endorphinergic genes (mu OPRM1 gene; proenkephalin [PENK, PENK polymorphic 3' UTR dinucleotide (CA) repeats]; GABergic gene (GABRB3), and dopaminergic genes (ANKKI Taq A; DRD2 C957T, DRD4 7R, COMT Val/met substation; MAO-A uVNTR; and SLC6A3 9 or 10R).
the DRD2 Taq1A polymorphism, which actually is located in the neighboring gene ANKK1).
DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking.
The so-called DRD2 gene has undergone a great deal of study, but the research has not been resolved as either implicating DRD2 as a cause of alcoholism, as a cause of some other psychiatric illness, or of no value at all.