CTSC

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CTSC

A gene on chromosome 11q14.2 that encodes cathepsin C, a ubiquitous lysosomal cysteine proteinase that co-ordinates activation of various serine proteinases (e.g., elastase, cathepsin G and granzymes A and B); it also activates neuraminidase and factor XIII. CTSC is highly expressed in the lungs, kidneys and placenta.

Molecular pathology
Defects in CTSC cause Papillon-Lefèvre syndrome, Haim-Munk syndrome and aggressive periodontititis type 1.
References in periodicals archive ?
The surveys were promoted via the DPPI website and disability, parenting and professional organisations.
DPPI is hoping to develop further training for health and social care professionals, and resources for both parents and professionals to improve outcomes for disabled parents.
Launched in 2002 by three former Jet Propulsion Laboratories' (JPL) engineers, DPPI has made significant strides in a short period of time.
DPPI") and Companhia Brasileira de Petroleo Ipiranga ("CBPI" and together with RPI and DPPI, the "Target Companies").
DPPI welcomes the opportunity to partner with AstraZeneca to find ways to ensure Delawareans the health coverage and services they need," said John H.
RPI DPPI CBPI Ordinary shares linked to the Shareholders Agreement 5,746,232 5,447,868 n.