DOPamine

dopamine /do·pa·mine/ (-mēn) a catecholamine formed in the body by the decarboxylation of dopa; it is an intermediate product in the synthesis of norepinephrine, and acts as a neurotransmitter in the central nervous system. The hydrochloride salt is used to correct hemodynamic balance in the treatment of shock and is also used as a cardiac stimulant.

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do·pa·mine (dp-mn)

n.

A monoamine neurotransmitter formed in the brain by the decarboxylation of dopa and essential to the normal functioning of the central nervous system. A reduction in its concentration within the brain is associated with Parkinson's disease. Also called 3-hydroxytyramine.

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Dopamine

A neurochemical made in the brain that is involved in many brain activities, including movement and emotion.

Mentioned in: Antidepressant Drugs, SSRI, Catecholamines Tests, Parkinson Disease, Weight Loss Drugs

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DOPamine

[dō′pəmin]

a naturally occurring sympathetic nervous system neurotransmitter that is the precursor of norepinephrine. It is produced in the substantia nigra and transmitted to the putamen and caudate nucleus. It has an inhibitory effect on movement. A depletion of dopamine produces the symptoms of rigidity, tremors, and bradykinesia that are characteristic of Parkinson's disease. It is available as an intravenously injectable drug. DOPamine has potent dopaminergic, beta-adrenergic, and alpha-adrenergic receptor activity. See also DOPamine hydrochloride.

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dopamine (dōˑ·p·mēn),

n a neurochemical that supports fine motor activity, blood pressure, focus, inspiration, intuition, enthusiasm, and joy, among other functions.

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dopamine

(dō´pmēn´),
n a sympathomimetic catecholamine used in the treatment of shock, hypotension, and low cardiac output.

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dopamine

a compound, hydroxytyramine, produced by the decarboxylation of dopa; an intermediate product in the synthesis of norepinephrine. It is a neurotransmitter in the central nervous system; administered intravenously to correct hemodynamic imbalance in shock syndrome.

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dopamine agonist

used to terminate pregnancy. See bromocriptine, cabergoline.

dopamine β-hydroxylase

enzyme catalyzing the synthesis of norepinephrine from dopamine. A copper-containing mono-oxygenase requiring vitamin C (ascorbic acid).

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dopamine

Neurology A catecholamine hormone and neurotransmitter essential to CNS activity; it is involved motor control, cognition, and reward; abnormal dopamine levels occur in Parkinson's disease, paranoia, memory and concentration defects; dopamine may modulate endorphin levels, altering perception of pain and pleasure; it restricts prolactin, affecting libido See Biogenic amine, Catecholamine, Indolamine, Serotonin.