aromatic d-amino acid decarboxylase

(redirected from DOPA decarboxylase)
Also found in: Acronyms.

ar·o·mat·ic d-a·mino ac·id de·car·box·yl·ase

(ar'ō-mat'ik dē a-mē'nō as'id dē'kar-boks'i-lās),
An enzyme that catalyzes the decarboxylation of l-dopa to dopamine, of l-tryptophan to tryptamine, and of l-hydroxytryptophan to serotonin; important in the biosynthetic pathway of catecholamines and melanin.

ar·o·mat·ic d-a·mi·no ac·id de·car·box·y·lase

(ār'ō-mat'ik ă-mē'nō as'id dē'kahr-bok'sil-ās)
An enzyme that catalyzes the decarboxylation of l-dopa to dopamine, of l-tryptophan to tryptamine, and of l-hydroxytryptophan to serotonin; important in the biosynthetic pathway of catecholamines and melanin.
References in periodicals archive ?
For the most part, available evidence from SPECT and PET studies of dopamine neuron terminal markers in ephedron addicts and in liver disease patients have confirmed the lack of an effect of elevated brain Mn on dopa decarboxylase activity using [[.
The product is being developed for the treatment of aromatic L-amino acid decarboxylase deficiency (AADC), a rare disease arising from mutations in the dopa decarboxylase (DDC) gene.
It has been previously shown that [beta]-cells take up L-DOPA (59) and that DOPA decarboxylase is active in pancreatic islet cells (60).
Measuring L-dopa in plasma and urine to monitor therapy of elderly patients with Parkinson's disease treated with L-dopa and a dopa decarboxylase inhibitor.