water sensor technology has completed testing by the USEPA for use in drinking water and environmental water.
Inhibition of cell proliferation, migration and invasion by DNAzyme
targeting MMP-9 in A549 cells.
Li created a DNAzyme
sensor that will be able to identify any bacteria, utilizing a method that doesn't require the steps and specialized equipment typically used to identify whether or not harmful bacteria are present.
In addition to the foregoing patent, Ribozyme has rights to over 20 patents that have issued in the United States covering various aspects of the DNAzyme
Atructure of 10-23 dnazyme
in complex with the target RNA in silicoa progress report on the mechanism of RNA cleavage by DNA enzyme
ANDalyze and Hach expand the availability of DNAzyme
testing technology for lead, copper, mercury, cadmium, zinc and uranium for drinking water, in a field portable product.
5 millimoles per litre, something the DNAzyme
community mostly ignores," says Dave Perrin, a bio-organic chemist at UBC.
The ANDalyze Lead100, catalytic DNA sensor uses a DNAzyme
reaction that fluoresces in the presence of lead.
Measuring the metal ions is done through a reaction that occurs when a water sample containing a target metal ion contaminant (such as cadmium) is introduced to a DNAzyme
sensor specific for that contaminant.
A single bound DNAzyme
can split many linkers, amplifying the signal and turning the solution from blue to red.
The catalytic DNAzyme
technology for this solution was developed in the laboratory of Dr.
McBryde Medal, sponsored by AB Sciex, for his research on aspects of aptamer and DNAzyme