DNA-RNA hybrid

DNA-RNA hy·brid

double-stranded polynucleic acids in which one strand is DNA and the other strand is the complementary RNA; formed during transcription and during multiplication of oncogenic RNA viruses.

DNA-RNA hy·brid

(hī'brid)
Double-stranded polynucleic acids in which one strand is DNA and the other strand is the complementary RNA; formed during transcription and during multiplication of oncogenic RNA viruses.
References in periodicals archive ?
Different studies suggest that transcription-associated recombination (TAR) is in large part due to collisions between transcription and replication, but increasing evidence indicate that R-loops, formed by a DNA-RNA hybrid and a displaced single-stranded DNA, may be a major determinant of genome instability.
Such a DNA-RNA hybrid would be resistant to both RNase and DNase activity.
The added sequence will bind up the messenger RNA with the same powerful bonding that holds together a DNA double helix, thus creating a freak double-stranded RNA or a DNA-RNA hybrid.
The H stands for hybrid, and this enzymatic activity degrades away the RNA pair of annealed DNA-RNA hybrids.
In each case, specific HPV DNA-RNA hybrids are formed.
Specificity, however, may be further improved because biotinylated oligonucleotides specific for HPV DNA sequences are used to capture HPV DNA-RNA hybrids (instead of anti-DNA-RNA polyclonal antibody used previously) onto streptavidine-coated wells of a microtiter plate.