RAD1

(redirected from DNA repair exonuclease rad1 homolog)

RAD1

A gene on chromosome 5p13.2 that encodes a protein of a heterotrimeric cell cycle checkpoint complex (9-1-1 complex), which is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites, where it attracts specialised DNA polymerases and other DNA repair effectors.
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