recombinant DNA

(redirected from DNA recombination)
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Related to DNA recombination: Homologous recombination

re·com·bi·nant DNA

altered DNA resulting from the insertion into the chain, by chemical, enzymatic, or biologic means, of a sequence (a whole or partial chain of DNA) not originally (biologically) present in that chain.

recombinant DNA

n. Abbr. rDNA
Genetically engineered DNA prepared by transplanting or splicing genes from one species into the cells of a host organism of a different species. Such DNA becomes part of the host's genetic makeup and is replicated.

recombinant DNA

a DNA molecule in which rearrangement of the genes has been experimentally induced. Enzymes are used to break isolated DNA molecules into fragments that are then rearranged in the desired sequence. DNA sequences from another organism of the same or a different species may also be introduced into the molecule, which is then replicated, resulting in both genotypic and phenotypic alterations in the organism that carries the recombinant DNA. See also genetic engineering.

recombinant DNA

DNA produced by the artificial linkage, in the laboratory or factory, of DNA from different sources. See also GENETIC ENGINEERING.

recombinant DNA

  1. DNA produced by joining together DNA sequences from different sources in vitro; often this involves VECTOR (2) DNA and foreign DNA to form a recombinant vector for use in GENETIC ENGINEERING.
  2. DNA produced by natural RECOMBINATION in vivo.

recombinant DNA

DNA transformed by insertion of a sequence of additional/foreign DNA
References in periodicals archive ?
D5: Gene Ontology contains regulation of DNA recombination and mitochondrion inheritance.
He has a PhD in pharmacology, with expertise in the areas of molecular biology, DNA recombination, gene and cell therapy, and protein purification.
He was one of three winners recognised by the Nobel Assembly for "a series of ground-breaking discoveries concerning embryonic stem cells and DNA recombination in mammals".
He was one of three winners given the award for a series of groundbreaking discoveries concerning embryonic stem cells and DNA recombination in mammals.
Epigenetic modifications contribute to locus accessibility and influence how lymphocytes specifically target the DNA recombination machinery to the antigen receptor genes, they specifically rearrange and express only one functional allele.
Sargent brings to the team more than 15 years scientific experience in the Molecular, Biology, Cellular Biology, Biochemistry and Genetics of DNA repair, DNA Recombination, and Deoxyribonucleotide Metabolism in Mammalian cells and bacteria to Advanced Cell Technology.