DNA polymerase inhibitor

DNA polymerase inhibitor

A drug that acts against viruses by interfering with the action of the enzymes viruses use to build up their own DNA. Examples of this class of drugs are acyclovir (Soothelip, Zovirax), ganciclovir (Cymevene, Virgan), valganciclovir (Valtrex) and foscarnet (Foscavir).
References in periodicals archive ?
The HBV DNA polymerase inhibitor entecavir has recently evolved as first line treatment predominantly because the development of virus strains resistant to entecavir is low compared to other antiviral agents.
Previous studies identified a nucleoside phosphonate DNA polymerase inhibitor, cidofovir (Vistide), as being active against poxviruses, including variola.