DNA laddering


Also found in: Wikipedia.

DNA laddering

The fragmentation of DNA that occurs during apoptosis.
Mentioned in ?
References in periodicals archive ?
Meanwhile, early and late apoptotic events via the Annexin V-FITC and DNA laddering assays, respectively.
Tenders are invited for DNA Laddering Kit (24) and 28 Other Items.
Assessment of DNA damage in bone marrow mesenchymal stem cells following Imidazole treatment by fast halo assay and DNA laddering assay.
Detection of DNA laddering in influenza virus infected HeLa cells: DNA laddering is commonly accepted as an important biochemical hallmark of apoptosis.
Following MAP treatment, apoptotic thymocytes showed TUNEL and CMI antibody positivity, DNA laddering and a 25-fold increase of DEVD-AFC cleavage (1.
Thus, although present in a small percentage of cells, DNA laddering from apoptotic cells was well below the detection limit of our biochemical method.
Apoptosis-related DNA laddering was visible after treatment of MCF-7 cells with increasing CSA concentrations for 48 h (Fig.
Apoptotic phenotypes including apoptotic body formation, DNA laddering, caspase 3 activation and cleavage of PARP proteins were induced by [CM.
To confirm these observations, A549/DDP cells apoptosis was also monitored by transmission electron microscopy and DNA laddering electrophoresis.
The occurrence of apoptosis mediated cell death was confirmed through the activation endonucleases-mediated nucleosome excision leading to the observation of DNA laddering of about 180-200 bp.
The DNA laddering was documented using an UV-transilluminator with CCD camera (UVBioDoc-It [TM] System, al-Biotech GmbH, Martinried, Germany).
However, administration of Coptidis Rhizoma extract prevented the DNA laddering caused by ischemia-reperfusion.