DDB1

(redirected from DNA damage-binding protein a)

DDB1

A gene on chromosome 11q12-q13 that encodes the large subunit of DNA damage-binding protein (a heterodimer composed of a large and a small (DDB2) subunit) that functions in nucleotide-excision repair.

Molecular pathology
DDB1 mutations have been tentatively linked xeroderma pigmentosum complementation group E (XPE).