RFX2

(redirected from DNA binding protein RFX2)

RFX2

A gene on chromosome 19p13.3-p13.2 that belongs to the regulatory factor X gene family, which encode transcription factors that contain a highly conserved winged-helix DNA-binding domain. RFX2 is structurally related to other regulatory factor (RF) family members—RFX1, RFX3, RFX4 and RFX5—and is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members, binding specifically to the X-boxes of MHC class-II genes.
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