DNMT3B(redirected from DNA MTase HsaIIIB)
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DNMT3BA gene on chromosome 20q11.2 that encodes a DNA methyltransferase thought to function in de novo methylation, rather than maintenance methylation. The protein localises to the cytoplasm and nucleus; its expression is developmentally regulated.
DNMT3B mutations cause immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome.