DNMT1

(redirected from DNA (cytosine-5-)-methyltransferase 1)

DNMT1

A gene on chromosome 19q13.2 that encodes a DNA (cytosine-5-)-methyltransferase 1, which methylates CpG residues and plays a critical role in establishing and regulating tissue-specific patterns of cytosine methylation.

Molecular pathology
Aberrant methylation patterns are associated with certain human tumours (e.g., breast carcinoma) and developmental
abnormalities.