DMSO


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DMSO

 
dimethyl sulfoxide, an industrial solvent that has the ability to penetrate plant and animal tissues and to preserve living cells during freezing. It has been used investigationally as an agent to increase the penetrability of other substances and as a topical analgesic and antiinflammatory. It has been approved by the U.S. Food and Drug Administration in a 50 per cent solution for direct instillation into the bladder for the treatment of interstitial cystitis. A 90 per cent solution, which has been approved only for veterinary use, is believed by some to be beneficial in the treatment of muscle sprains and strains, arthritis, spinal cord injuries, and the aftereffects of stroke when it is applied externally and absorbed by the skin. Claims that it is effective for treating these disorders in humans have not been validated by research studies. It has been shown to produce some short-term side effects.

DMSO

Abbreviation for dimethyl sulfoxide.

DMSO

dimethyl sulfoxide.

DMSO

(dē′ĕm-ĕs-ō′)
n.
A colorless hygroscopic liquid, (CH3)2SO, obtained from lignin, used as an industrial solvent and in medicine as a penetrant to convey medications into the tissues.

DMSO

abbreviation for dimethyl sulfoxide.

DMSO

Alternative medicine
A substance that occurs naturally in minute amounts in certain foods, which has industrial and health-related applications. Animal studies have shown it to have analgesic, anti-inflammatory, antimicrobial, vasodilatory and other properties; up to the 1960s, DMSO had been administered orally, topically or parenterally by mainstream physicians for various conditions, including arthritis, bursitis, cancer, emphysema, mental illness and pain. In the face of its association with lenticular degeneration, DMSO was removed from general use; some practitioners of alternative healthcare continue to recommend DMSO for these and other uses.
 
Toxicity
Topical DMSO is associated burning, itching and an unpleasant odour.
 
Mainstream medicine
DMSO is FDA-approved for treating interstitial cystitis, and may be of use in treating scleroderma, sprains, arthritis, cerebrovascular accidents, familial amyloidotic polyneuropathy and acetaminophen hepatotoxicity. DMSO reduces the ice crystals formed in frozen section tissues from the operating suite, and may be an effective cryopreservative.

DMSO

Abbreviation for dimethyl sulfoxide.

DMSO,

DMSO

Abbreviation for dimethyl sulfoxide.

DMSO

dimethyl sulfoxide, an industrial solvent that has the ability to penetrate plant and animal tissues and to preserve living cells during freezing. It has bacteriostatic, anti-inflammatory, analgesic, radioprotective, fibrinolytic and vasodilative properties, and inhibits cholinesterase and granulation tissue. DMSO also has been used as an agent to increase the penetrability of other substances. Only approved for veterinary use, it has found varied applications as a topical treatment for musculoskeletal conditions in horses and skin diseases, mainly in dogs.
References in periodicals archive ?
Public demand for DMSO grew strong and the FDA went on the defensive after millions watched Dr.
The SYBR 14 stock solution contained 1 mM of dye in 100 [micro]L of DMSO.
Having the rear DMSO operate from the LOGPAD during combat operations had its advantages.
IBUFOAM is a topical ibuprofen foam formulation that combines a transdermal carrier DMSO with 5% the NSAID ibuprofen and delivers the active drug through the skin directly to the site of inflammation and pain.
EG and DMSO are the most commonly used permeable cryoprotectants in vitrification; EG has highest permeability due to lowest molecular weight compared with DMSO (62.
2]-g-PMMA nanoparticles prepared via the radical grafting polymerization in DMSO at 90[degrees]C for 16 h with various CuS[O.
Mevcut literetur verileri isiginda; primer mesane amiloidozu saptanan hastalarda TUR sonrast intravezikal DMSO tedavisi ve oral kolsisin tedavisi onerilmektedir.
The data (log fold ratio over DMSO control) from both the 24-hr and 65-hr exposure intervals were used to predict mammalian reproductive toxicity.
Conversion of DDT and distribution of dechlorinated products in pyridine and DMSO were examined by means of controlled potential electrolysis combined with GC-MS analysis.
Compounds 4-6, 11, 15, 17-22, 37-42, 46 and standard antimicrobial agents (chloramphenicol and terbinafin were used as standard antibacterial and antifungal agents, respectively) were dissolved in DMSO to get the required quantities of 5 mg/mL concentration.
3]/100 g, 5-80 phr of at least one mineral oil plasticizer that has a content of polycyclic aromatic compounds determined with the DMSO extract according to the IP 346 method of less than 3% by weight relative to the total weight of the mineral oil plasticizer, and 5-30 phr of at least one resin with an average molecular weight determined with GPC of less than 400 g/mol and a softening point (ring and ball according to ASTM E 28) of less than 40[degrees]C.