NEO1

(redirected from DKFZp547B146)

NEO1

A gene on chromosome 15q22.3-q23 that encodes a cell surface protein belonging to the immunoglobulin superfamily, the C-terminal internal domain of which shares homology with the tumour suppressor gene DCC and is involved in cell growth, differentiation and cell–cell adhesion.

Molecular pathology
NEO1 mutations are associated with cell proliferation in certain cancers.