DIDMOAD


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DIDMOAD

An acronym for Wolfram syndrome, which comprises diabetes insipidus, diabetes mellitus, optic atrophy, and deafness.
An autosomal recessive [MIM 222300] condition characterised by diabetes insipidus, non-autoimmune type 1 diabetes mellitus, optic atrophy, sensorineural deafness and further neurological and endocrinological abnormalities. Death occurs prematurely, often from respiratory failure associated with brainstem atrophy