deafness autosomal recessive type 21

(redirected from DFNB21)

deafness autosomal recessive type 21

An autosomal recessive form (OMIM:603629) of nonsyndromic sensorineural deafness.
 
Molecular pathology
Caused by defects of TECTA, which encodes alpha tectorin, a major non-collagenous protein of the tectorial membrane of the inner ear that contacts the stereocilia bundles of sensory hair cells.