deafness autosomal dominant type 12

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deafness autosomal dominant type 12

An autosomal dominant form (OMIM:601543) of nonsyndromic sensorineural deafness. 

Molecular pathology
Caused by defects of TECTA, which encodes alpha tectorin, a major non-collagenous protein of the tectorial membrane of the inner ear that contacts the stereocilia bundles of sensory hair cells.