ACTG1

(redirected from DFNA20)

ACTG1

A gene on chromosome 17q25 that encodes a gamma actin which coexists with beta actin as a cytoskeletal component and mediator of internal cell motility. Actin gamma 1 is a cytoplasmic actin found in non-muscle cells.

Molecular pathology
ACTG1 mutations are associated with DFNA20/26, a type of autosomal dominant, non-syndromic sensorineural progressive hearing loss.