Patti Negri, a 46-year-old Hollywood resident and DES daughter
, entered a menopausal state at age 15 and was unable to have children.
Anyone who saw A Healthy Baby Girl already knows Helfand's family; her first film was a personal saga about the cancer she survived as a DES daughter
A DES daughter
activist, she has written a documentary, "Wonder Drug" about the DES fallout.
She was co-counsel in the first DES daughter
case, Bichler v Lilly, and has written, testified and lectured about obstetrical malpractice, unnecessary hysterectomies and product liability litigation.
A DES daughter
has a one in 1,000 risk of developing clear cell carcinoma, about 40 times that of a non-exposed women.
When McCarthy discovered in 2005 that she had been exposed to the drug in utero, she researched DES and its potential ramifications which include a rare vaginal cancer in DES daughters
, and an increase in the risk of breast cancer in DES daughters
and testicular cancer in DES sons.
1) Unfortunately, DES not only did not work to prevent miscarriage, but it also caused severe medical problems for both the women who took the drug and their children who were exposed to the drug in utero, who are known as DES Daughters
and DES Sons.
Researchers have also found that DES daughters
are 40 times more likely to develop cancer of the vagina and cervix than women who were not exposed to the drug.
1980), reporting that DES daughters
had elevated levels of serum testosterone (Wu et al.
When cancer was eventually found in DES daughters
, it was clear that the animal studies did in fact predict these cancerous changes much earlier.
may have fertility and pregnancy problems and should be checked for rare cancers, called clear cell adenomas, of the cervix and vagina.
Now Dutch researchers want to establish any connection between DES daughters
and the risk of cancer during and after menopause.