DDR2


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DDR2

A gene on chromosome 1q23.3 that encodes a receptor tyrosine kinase belonging to the subfamily homologous to Dictyostelium discoideum protein discoidin (Discoidin Domain-containing Receptor); it is required for normal bone development. DDR2 regulates osteoblast differentiation and chondrocyte maturation via a MAP kinase-signalling pathway, activating the transcription factor RUNX2; it regulates remodelling of the extracellular matrix by upregulating collagenases MMP1, MMP2 and MMP13, facilitating cell migration and tumour cell invasion. DDR2 promotes fibroblast migration and proliferation, contributing to wound healing.
References in periodicals archive ?
So a drug that blocks DDR2 from binding with collagen won't destroy the tumor, but it could inhibit the invasion of these tumors into surrounding tissue and reduce metastasis.
Micron has maintained a high-level of quality in delivering DDR2 memory for customers, offering premium performance and multiple configurations, densities, and package options.
NVIDIA CUDA and PhysX technologies enable the ZOTAC GeForce 9400GT Synergy Edition and GeForce 9400GT DDR2 1GB to have enhanced functions.
Elpida 512 Megabyte DDR2 SO-DIMMs are currently available in samples.
DDR2 modules were developed to support the latest motherboards and systems as they are released.
Northwest Logic's DDR2 SDRAM Memory Interface Solution combines Northwest Logic's high-performance, fully featured DDR2 SDRAM Controller with its eASIC-specific DDR PHY.
It has also updated HyperX 800-MHz (PC6400) CL4 DDR2 to support 4-4-4-12 in 512MB, 1GB modules and 1GB, 2GB kit memory configurations.
4 Gigabyte DDR2 Registered DIMMs provide the highest density available for high volume and server blade applications," said Jun Kitano, director of Technical Marketing for Elpida Memory (USA).
The Intelli DDR solutions are implemented in several SDR and DDR protocols, including SDRAM and Mobile SDRAM, as well as MobileDDR, DDR1 and DDR2 at several foundries on a variety of process nodes.
TELECOMWORLDWIRE-14 October 2005-Kingston launches 667- MHz DDR2 memory(C)1994-2005 M2 COMMUNICATIONS LTD http://www.
Worldwide Computer Products News-14 October 2005-Kingston launches 667- MHz DDR2 memory(C)1995-2005 M2 COMMUNICATIONS LTD http://www.
a leader in advanced memory technology, has announced sample production of the next-generation memory module for servers and workstations--a fully buffered, dual in-line memory module (FB DIMM) based on DDR2 technology.