DDR2


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DDR2

A gene on chromosome 1q23.3 that encodes a receptor tyrosine kinase belonging to the subfamily homologous to Dictyostelium discoideum protein discoidin (Discoidin Domain-containing Receptor); it is required for normal bone development. DDR2 regulates osteoblast differentiation and chondrocyte maturation via a MAP kinase-signalling pathway, activating the transcription factor RUNX2; it regulates remodelling of the extracellular matrix by upregulating collagenases MMP1, MMP2 and MMP13, facilitating cell migration and tumour cell invasion. DDR2 promotes fibroblast migration and proliferation, contributing to wound healing.
References in periodicals archive ?
So a drug that blocks DDR2 from binding with collagen won't destroy the tumor, but it could inhibit the invasion of these tumors into surrounding tissue and reduce metastasis.
Micron has maintained a high-level of quality in delivering DDR2 memory for customers, offering premium performance and multiple configurations, densities, and package options.
NVIDIA CUDA and PhysX technologies enable the ZOTAC GeForce 9400GT Synergy Edition and GeForce 9400GT DDR2 1GB to have enhanced functions.
The models offer built-in coverage and can be configured to turn on/off initialization, enable/disable DDR2 interface checkers and coverage.
As DDR2 memory becomes widely adopted during 2004, it will be used to improve performance on desktops, notebooks, and servers as well as telecommunication and networking devices.
This press release contains forward-looking statements regarding the production of Micron's new DDR2 and DDR3 Aspen Memory modules.
The development of HDTV and its requirement for low-cost, high-memory bandwidth has created demand for high performance DDR2 memory interfaces.
Memory products manufacturer Kingston Technology Company Inc has revealed that it has expanded its Ultra Low Latency DDR modules and introduced Low Latency DDR2 memory modules.
4 Gigabyte DDR2 Registered DIMMs provide the highest density available for high volume and server blade applications," said Jun Kitano, director of Technical Marketing for Elpida Memory (USA).
Samsung Semiconductor, the world leader in advanced memory technology and the leading producer of DRAM (dynamic random access memory), announced today that it is now mass producing the lowest powered, highest density DDR2 memory available for servers.
Kingston's new high frequency HyperX DDR2 9600's (1.
Worldwide Computer Products News-14 October 2005-Kingston launches 667- MHz DDR2 memory(C)1995-2005 M2 COMMUNICATIONS LTD http://www.