DDB2

DDB2

A gene on chromosome 11p12-p11 that encodes a protein necessary for the repair of UV-light-damaged DNA, which is the small subunit of DNA damage-binding protein (a heterodimer composed of a large (DDB1) and a small subunit) that functions in nucleotide-excision repair.

Molecular pathology
DDB2 mutations have been tentatively linked xeroderma pigmentosum complementation group E (XPE).
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Genes Tested AtP ALK APC ATM BAP1 BRCA2 BRIP1 BUB1B CDC73 CDH1 CEP57 CHEK2 CYLD DDB2 DICER1 ERCC3 ERCC4 ERCC5 EXT1 EXT2 FANCD2 FANCE FANCF FANCG FANCI GATA2 GPC3 HNF1A HOXB13 HRAS MLH1 MHS2 MSH6 MUTYH NBN PHOX2B PMS1 PMS2 PPM1D PRF1 RAD51D RBI RECQL4 RET RHBDF2 SDHC SDHD SLX4 SMAD4 SMARCA4 TP53 TSC1 TSC2 VHL WT1 BARD1 BLM BMPR1A BRCA1 CDK4 CDKN1C CDKN2A CEBPA DI53L2 EGFR EPCAM ERCC2 EZH2 FANCA FANCB FANCC FANCL FANCM FH FLCN KIT MAX MEN1 MET NF1 NF2 NSD1 PALB2 PRKAR1A PTCH1 PTEN RAD51C RUN XI SBDS SDHAF2 SDHB SMARCB1 STK11 5UFU TMEM127 WRN XPA XPC This chart shows all 98 cancer susceptible genes included in this new test.
Otro de los problemas cruciales sobre los que no se pudo profundizar, fue sobre el impacto que tiene el ejercicio fisico en los marcadores tumorales asociados al cancer de mama [ErbB-2, P53 FOSFOPROTEINA, proliferacion celular (Ki67), BRCA1, PCNA, receptores hormonales ER/PR, Bcl-2, DDB2 proteina, P27 PROTEINA, SKP2, IGF1, IGF2, IGFBP1-3, Estradiol] y de esta forma plantear las posibles vias y mecanismos biologicos de accion.
DDB2 is the employee's deemed death benefit at the end of the policy year; DDB1 is the employee's deemed death benefit at the end of the preceding policy year; and X is the premium for one dollar of paid-up whole life insurance at the employee's attained age at the beginning of the policy year.