D-zone test | definition of D-zone test by Medical dictionary
D-zone test (zōn test)
Assessment tool used to detect inducible clindamycin resistance in staphylococci and beta-hemolytic streptococci.
References in periodicals archive
The D-zone test for inducible clindamycin resistance was performed for isolates resistant to erythromycin and susceptible to clindamycin by single-agent testing (11).
Of all CC1 isolates, 16/25 (64%) were resistant to clindamycin; 14/16 (88%) were not susceptible by virtue of a positive D-zone test result.
A D-zone test confirmed the presence of iMLSB in the pre-treatment isolate.
Validation of the D-zone test starts with standard testing of both clindamycin and erythromycin disks by normal quality-control procedures to assure appropriate antibiotic concentration.