Initially referred to as Lamb Nephrosis due to one of the main post-mortem features affecting the kidneys, it is now suggested that it be named Lamb D-Lactic Acidosis
Syndrome (LDLAS) - although it is most likely that it will still continue to be referred to as 'drunken lambs'.
Causes of increased anion gap metabolic acidosis L-lactic acidosis Propylene glycol D-lactic acidosis
Aspirin overdose Ketoacidosis Toluene Alcohol Pyroglutamic acid Methanol Ethylene glycol Table 2.
Because only L-lactate is routinely analyzed in most laboratories, an unrecognized D-lactic acidosis can have severe neurological consequences if not diagnosed and treated promptly.
Most routine clinical chemistry laboratories do not assay D-lactic acid; thus, a diagnosis of D-lactic acidosis may be delayed.
D-Lactic acidosis in a man with the small bowel syndrome.
D-Lactic acidosis in two patients with short bowel syndrome: bacteriological analyses of the fecal flora.
The new additions are D-lactic acidosis
, typically seen in patients with short gut syndromes; the accumulation of propylene glycol, a common diluent for intravenous medications; and 5-oxoproline, an increasingly recognized disorder most commonly associated with chronic acetaminophen ingestion.
Dietary management of D-lactic acidosis
in short bowel syndrome.