glucuronic acid

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Related to D-glucuronic acid: glucuronic acid pathway

glucuronic acid

 [gloo″ku-ron´ik]
a uronic acid formed by oxidation of C-6 of glucose to a carboxy group; it occurs in proteoglycans (mucopolysaccharides), and is important in the conjugation of xenobiotics; it is conjugated to many poisons and drugs by the liver, forming glucuronides, which markedly decreases their toxicity and enhances their excretion by the liver, intestine, and kidney.

glu·cu·ron·ic ac·id

(glū'kū-ron'ik as'id),
The uronic acid of glucose in which C-6 is oxidized to a carboxyl group; the d-isomer detoxicates or inactivates various substances (for example, benzoic acid, phenol, camphor, and the female sex hormones) undergoing conjugation with such substances in the liver, the glucuronides so formed being excreted in the urine.

glucuronic acid

/glu·cu·ron·ic ac·id/ (gloo-ku-ron´ik) the uronic acid derived from glucose; it is a constituent of several glycosaminoglycans and also forms conjugates (glucuronides) with drugs and toxins in their biotransformation.

glu·cu·ron·ic ac·id

(glū'kyūr-on'ik as'id)
The uronic acid of glucose in which C-6 is oxidized to a carboxyl group; the d-isomer detoxicates or inactivates various substances (e.g., benzoic acid, phenol, camphor, and the female sex hormones), the glucuronides so formed being excreted in the urine.

glucuronic acid

A substance formed from glucose that combines with many body waste products to form glycosides that are excreted in the urine.

glucuronic acid

a uronic acid formed by oxidation of C-6 of glucose to a carboxy group; it occurs in proteoglycans (mucopolysaccharides), and is conjugated in the liver with many natural and foreign compounds or their metabolites, forming glucuronides, which are excreted in the urine.

glucuronic acid pathway