cycloserine

(redirected from D-cycloserine)
Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

cycloserine

 [si″klo-ser´ēn]
an antibiotic elaborated by Streptomyces orchidaceus or produced synthetically, used as a tuberculostatic and in the treatment of urinary tract infections.

cy·clo·ser·ine

(sī'klō-ser'ēn),
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.
Synonym(s): orientomycin

cycloserine

/cy·clo·ser·ine/ (-sĕ´rēn) an antibiotic produced by Streptomyces orchidaceus or obtained synthetically; used as a tuberculostatic and in treatment of urinary tract infections.

cycloserine

(sī′klō-sĕr′ēn)
n.
An antibiotic effective against a wide range of bacteria, used especially in the treatment of tuberculosis and infections of the urinary tract.

cycloSERINE

[sī′klōser′ēn]
an antibiotic.
indications It is prescribed in the treatment of active pulmonary and extrapulmonary tuberculosis.
contraindications Epilepsy, depression, severe anxiety, psychosis, severe renal insufficiency, excessive concurrent use of alcohol, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the most serious reactions are central nervous system toxic effects, including tremor, drowsiness, convulsions, and psychotic changes. Pyridoxine may be given concurrently to prevent these effects. Other side effects include arrhythmias and optic neuritis.

cycloserine

Infectious disease A broad-spectrum antibiotic used for UTIs and TB Adverse effects CNS Sx, allergy, skin rash, ↑ LFTs

cy·clo·ser·ine

(sī'klō-ser'ēn)
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.

cycloserine

A drug used to treat TUBERCULOSIS caused by organisms resistant to treatment by standard drugs such as rifampicin, isoniazid, ethambutol and streptomycin. The drug is on the WHO official list.

cy·clo·ser·ine

(sī'klō-ser'ēn)
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.

cycloserine (sī´klōserēn),

n brand name: Seromycin Pulvules;
drug class: antitubercular;
action: inhibits cell wall synthesis, analog of D-alanine;
uses: pulmonary tuberculosis.
References in periodicals archive ?
This report is the second independent, peer-reviewed confirmation of the potential value of D-cycloserine in extending the effect of Ketamine in the treatment of acute depression.
The use of D-cycloserine in treating anxiety disorders, such as phobias, appears to have significant clinical implications -- namely its potential to augment psychotherapy and enhance learning," said Dr.
Our study will examine the potential for individual doses of D-cycloserine to speed treatment and improve response to exposure-based treatment for panic disorder,' he said.
In addition to the above the report determines d-cycloserine consumers in the market.
Urbano and her colleagues conducted a 10-week uncontrolled, randomized, double-blind trial comparing D-cycloserine once daily at 50 mg or once weekly at 50 mg for 8 weeks in 20 patients with ASD.
D-cycloserine also binds to the NMDA receptor and, according to animal studies, enhances learning.
We didn't see much evidence today that D-cycloserine boosts the therapeutic benefit of cognitive-behavioral therapy [CBT] in PTSD," agreed Dr.
Major pharmaceutical firms have been developing NMDA receptor modulators for more than 20 years, and a few, including Memantine, ketamine, D-cycloserine, and dextromethorphan are on the market, generating annual sales of more than $1 billion.
AMSTERDAM -- The N-methyl-D-aspartate partial agonist D-cycloserine might enhance the results of exposure therapy, especially when it is properly timed and dosed, according to a leading researcher in this field.
A randomized, double-blind study is currently underway, pitting d-cycloserine, a partial agonist of the N-methyl-D-Aspartate (NMDA) glutamate receptor subtype, against placebo, Dr.
D-cycloserine Technology Discovered at the Emory University School of Medicine
In one study, investigators found that D-cycloserine for obsessive-compulsive disorder (OCD) increases therapeutic learning, accelerates fear extinction in early sessions, and reduces the number of exposure sessions required for a good outcome, reported Matt Kushner, Ph.