cytotoxic T cell

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Related to Cytotoxic T-lymphocyte: Killer T cells, CD8+ cell

cytotoxic T cell

cytotoxic T cell

See CD8 cell.

cytotoxic T cell

A CD8+ T lymphocyte that can destroy microorganisms directly through the release of perforin and proteolytic enzymes. These cells are particularly important in the defense against viruses, rejection of allografts, and, possibly, new malignant cells. Synonym: CD8 cell; cytotoxic cel; killer T cell
See also: cell
References in periodicals archive ?
Because these foreign proteins are produced inside the patients' cells, the product elicits a cytotoxic T-lymphocyte (CTL) response rather than an antibody response.
Pink Sheets:BQST) announced today that European Patent Number 0671947 titled "Compositions For Eliciting Cytotoxic T-Lymphocyte Responses Against Viruses" has been awarded to the Board of Regents The University of Texas System.
Findings demonstrated that mice vaccinated with dendritic cells pulsed with FLK-1 protein had a high level of anti-FLK-1 antibody and cytotoxic T-lymphocyte activity.
By producing HIV antigens intracellularly, the drug is designed to stimulate a patient's immune system to mount a cytotoxic T-lymphocyte (CTL), or killer T-cell, response directed against HIV infected cells.
Our investigations also confirm the significance of the activity of cytotoxic T-lymphocytes for the healing process in elderly persons with MSF.
Cytotoxic T-lymphocytes (CTL) specific to cytomegalovirus (CMV) antigens decline significantly during the first 6 months following liver transplantation, a finding that may explain the increased vulnerability to CMV observed in this patient population.
For this reason, many researchers are trying to create vaccines that stimulate cytotoxic T-lymphocytes (CTLs), immune-system cells that kill virus-infected cells in the body.
Recently, her research group studied how TCDD affects a mouse's production of cytotoxic T-lymphocytes, which destroy cells infected with viral invaders.
T cells, secretory immunoglobulin A (S-IgA), and antigen-specific cytotoxic T-lymphocytes (CTLs).