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Cytokines

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Cytokines
Chemicals made by the cells that act on other cells to stimulate or inhibit their function. Cytokines that stimulate growth are called "growth factors."

cytokines (sīˑ·tō·kīnz),
n.pl regulatory proteins, such as lymphokines and interleukins that are produced by immune system cells and act as intercellular mediators in the modulation of immune response. Cytokines produced by recombinant DNA technology are administered to people to affect immune status.

amplification system
Physiology A generic term for any group of proteins that function in coordinated sequences, forming positive feedback loops for expanding the response to a low intensity signal
Amplification systems
Coagulation,
eg factor Xa activating factor 'X' in the presence of factor VIII, Ca2+, and phospholipid
Complement
Augments B-cell response. See Alternative and Classic pathways
Cytokines
Amplifies T-cell response, ILs, kinins, lipid mediators and mast cell products
.


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Alcohol's effects continue long after the party is over: some cytokines were still not on full duty guarding against infection 24 hours after the binge.
BACKGROUND/AIMS: Clinical studies indicate that primary proinflammatory cytokines, such as interleukin-1beta (IL-1beta) are elevated in the gingival crevice around teeth with periodontitis but the secondary cytokines and chemokines, IL-6 and IL-8, are not.
When this modified toxin was added to human cells grown in culture, it inhibited the release of cytokines and mucin, suggesting that it could be used to treat asthma and cancers.
 
 
 
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