IL29

(redirected from Cytokine Zcyto21)

IL29

A gene on chromosome 19q13.13 that encodes interleukin-29, an immunomodulatory cytokine which upregulates MHC class-I antigen expression. It has potent antiviral activity and has antitumour activity. IL29 is a ligand for the heterodimeric class-II cytokine receptor composed of IL10RB and IL28RA, which is thought to act via the JAK-STAT pathway.
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